Most papers are machine-translated to English; some are originally in English.
Showing 29 of 79 papers in Medicine, Pharmacy
Background Under the government's high attention to the development of general practice, tertiary general hospitals have successively established general practice departments. The disciplinary characteristics of general practice departments give them significant advantages in the admission and manag…
Background Hemorrhoids are one of the common diseases in colorectal and anal surgery, and injection therapy is a commonly used treatment modality. However, nationwide data regarding the depth of application and standardized usage of injection therapy are currently lacking, necessitating this investi…
Background: With the continuous deepening of the family doctor contract service system, how to effectively extend family doctor contract services to functional building populations has emerged as a key focus. Understanding the demand characteristics of this population is a critical approach for deve…
Immune-mediated inflammatory diseases (IMIDs) commonly affect women of childbearing age, and the impact of therapeutic agents on pregnancy outcomes, fetal development, and infants complicates pharmacotherapeutic decision-making during pregnancy and lactation. This article reviews the latest domestic…
Background: The application of deep learning in medical imaging faces challenges such as time-consuming and labor-intensive data annotation, which restricts the efficiency of its clinical translation. Objective: To investigate the feasibility and efficacy of a deep learning network that integrates t…
Background In recent years, medical research has identified a certain association between Relative Fat Mass (RFM) and cardiovascular disease (CVD). However, nationwide cohort studies on the relationship between RFM and CVD incidence risk in Chinese populations remain limited. Objective To analyze th…
Stroke represents one of the principal causes of the global burden of disease and mortality, concurrently ranking as the leading cause of death in the Chinese population, and has emerged as a major public health problem threatening public health and social development. Prior research has demonstrate…
Background Cancer patients often develop symptoms such as muscle wasting, yet the underlying pathological mechanisms remain incompletely elucidated. Objective To investigate the pathological mechanisms of cancer-associated skeletal muscle injury and to examine the therapeutic effect of the Yiqi Chut…
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are respiratory diseases with high incidence and mortality. COPD is an independent high-risk factor for LC, and the two conditions influence each other, posing challenges to clinical diagnosis and treatment. Early detection and treatm…
Obesity is frequently complicated by metabolism-related diseases, which constitute important etiological factors or risk factors and are associated with adverse prognosis; effective weight reduction can improve or even remit these comorbidities. Lifestyle intervention alone demonstrates suboptimal e…
Background: As an emerging technology, large language models are gradually gaining recognition and application among the general public. Thyroid cancer is a common type of malignant tumor in China, and patients have a high demand for thyroid cancer popular science information; however, there is stil…
Background: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) constitutes a common complication of rheumatoid arthritis (RA), affecting 20%~50% of RA patients and substantially increasing mortality risk. Currently, clinically effective and safe therapeutic agents with clear targets …
Background IgA vasculitis nephritis (IgAVN) represents one of the common systemic small-vessel vasculitides in childhood, yet comprehensive investigations into the relationship between hematological indices and urinary protein quantification in pediatric patients remain limited. Objective This study…
Background: Polycystic ovary syndrome (PCOS) is an extremely prevalent endocrine disorder among women of reproductive age. Obese PCOS patients often present with insulin resistance, leading to disturbances in glucose and lipid metabolism, abnormal pancreatic islet function, which subsequently causes…
Background: Cardiometabolic diseases are closely associated with depression. Primary care management of cardiometabolic diseases has achieved initial scale; however, there is insufficient attention to psychological issues such as depression in patients, and a lack of simple, accurate, and efficient …
Cerebral ischemia-reperfusion injury refers to the secondary damage to ischemic brain tissue that occurs during the restoration of cerebral blood flow following interruption, resulting from multiple biological processes including energy metabolism disturbance, oxidative stress, free radical damage, …
Background: The "3+2" order-oriented assistant general practitioners in Jiangsu Province play an important role in primary healthcare, but face issues such as low contract fulfillment rates and insufficient professional identity, urgently needing to improve work well-being. Objective: To understand …
Background: Patients with interstitial lung disease are prone to acute exacerbations, with infection being one of the important triggers. Patients experiencing acute exacerbation have high mortality rates and poor prognosis, and research on this population is currently limited in China. Objective: T…
Background: Training rural order-directed medical students is an important measure to alleviate the shortage of rural medical human resources. As of October 2023, three cohorts of order-directed medical graduates have completed their required service obligations. However, there is a lack of systemat…
Background The incidence of diabetes is increasing year by year. China has incorporated the management of type 2 diabetes as an important disease category into community basic health services; however, gaps remain in standardized grassroots diabetes management, particularly regarding quality and cap…
Background With population aging and an increasing proportion of chronic disease patients, public demand for primary healthcare resources is becoming increasingly diversified and complex. Demand for primary healthcare resources varies across different regions and populations, and some areas face sho…
Familial hypercholesterolemia (FH) is a severe inherited metabolic disorder, among which homozygous FH (HoFH) is rare and particularly severe. Early screening, diagnosis, and treatment can substantially improve patient prognosis; however, the recognition and management of HoFH remain severely inadeq…
Background: Osteoporosis (OP) is a systemic bone disease characterized by reduced bone mass, destruction of bone microarchitecture, increased bone fragility, and susceptibility to fracture. China has a large population of OP patients. With advancing age, not only is bone health compromised, but musc…
Background Locally advanced gastric cancer primarily includes stage III gastric cancer, which is mainly managed with comprehensive therapy. Postoperative recurrence is a key factor affecting patient prognosis. Objective To investigate the factors influencing long-term prognosis in stage III gastric …
Objective. To investigate the principal differential metabolites of Xihuang Pill (XHP) in rat serum and the mechanism of related metabolic pathways in breast cancer. Methods. Metabolites in the XHP drug serum group and blank serum group were analyzed qualitatively and quantitatively using liquid chr…
Cardiovascular disease (CVD) is the leading cause of mortality in China and worldwide, and lipid metabolism disorders are important risk factors for CVD. Understanding the prevalence of dyslipidemia during childhood and adolescence facilitates early prevention of dyslipidemia in adulthood. Objective…
Background Hierarchical medical system is one of the primary objectives of healthcare reform. The Guidance on Promoting the Construction of Hierarchical Medical System (Guobanfa [2015] No. 70) issued by the General Office of the State Council in 2015 proposed that the proportion of outpatient visits…
Background Chronic diseases have become a major public health problem affecting population health. The number of chronic disease patients in China continues to increase, the number of deaths is rising year by year, and the disease burden on patients is gradually intensifying. Understanding the chang…
Background Liver macrophages play crucial roles in constructing host defense mechanisms and maintaining internal environmental homeostasis, and represent important cellular components involved in liver injury and repair. Monocyte-derived macrophages differ from liver resident macrophages in terms of…
