Most papers are machine-translated to English; some are originally in English.
Showing 44 of 44 papers in Medicine And Pharmacy
Background: Globally, children still face challenges of early developmental delays. The characteristics and differences of early childhood development (ECD) in economically developed regions remain unclear. Conducting ECD-related analyses based on existing child health management system databases ca…
Background Primary Sjögren's disease (pSjD) is a chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, mainly manifesting as dry mouth and dry eyes, and can involve multiple systems. Epidemiological surveys show its prevalence is approximately 0.06%~0.08%, and is i…
Background As population aging intensifies in China, the issue of frailty among older adults has become increasingly prominent, rendering research on its prevention and intervention particularly critical. Currently, most studies have not explored the dynamic relationship between physical activity tr…
Background Currently, hospital physical examination centers and communities primarily employ fasting plasma glucose and glycated hemoglobin as indicators for assessing blood glucose levels. Existing studies have investigated the diagnostic value of these two indicators when used alone or in combinat…
Background: Malignant pleural effusion represents a critical indicator of advanced-stage malignancy and metastasis. Current diagnostic modalities for characterizing pleural effusion exhibit limitations that preclude timely and effective determination of effusion nature. The majority of malignant ple…
Background In China, college students have become a high-risk population for depression. Maladaptive attentional bias and interpretive bias constitute important factors in the onset and maintenance of depression. While previous studies have examined the characteristics of attentional bias and interp…
To address the global issue of regional imbalance in health workforce distribution, numerous governments worldwide have implemented diversified talent cultivation programs tailored to their national contexts. Since 2010, China has promulgated the free training policy for rural order-directed medical…
Acute myocardial infarction (AMI), as one of the leading causes of mortality and disability from cardiovascular disease globally, has made the optimization of its postoperative long-term management strategies a focal issue in the medical community. Exercise-based cardiac rehabilitation (EBCR), as a …
Heart failure represents the end-stage manifestation of multiple cardiac diseases with a poor prognosis, and its risk of onset increases significantly with advancing age and cardiomyocyte senescence. The mammalian target of rapamycin (mTOR) pathway plays a pivotal role in the pathophysiology of card…
This paper focuses on the issue of delayed completion in standardized general practice residency training (GP residency training), conducting a cross-national comparative analysis of the training systems, current status of delays, causes, and reform strategies in 11 representative developed and deve…
Background: In clinical practice, children with asthma-related symptoms such as wheezing, cough, and chest tightness first undergo pulmonary ventilation function testing. When forced expiratory volume in the first second (FEV1) <70%, it indicates significant airflow limitation or airway obstruction,…
Amidst the global wave of digital transformation, the data revolution in the healthcare industry is accelerating, with countries actively introducing digital policies to drive medical data development. This paper focuses on the construction of digital policy-driven medical data spaces, systematicall…
Hypertension is the leading cause of stroke mortality and the primary contributor to the burden of stroke-related disability-adjusted life years (DALYs). As the most important modifiable risk factor, effective prevention and control of hypertension has become a core task in primary and secondary str…
Background As understanding of endometriosis pain management deepens, an increasing number of domestic and international guidelines/expert consensuses have emerged, providing important guidance and reference for clinical practice. However, their quality varies considerably, necessitating systematic …
The application of artificial intelligence in the medical domain has emerged as a pivotal driving force for bridging the chasm between basic research and clinical practice, concurrently reshaping diagnostic and therapeutic paradigms. While transforming medical decision-making workflows and doctor-pa…
Background The diagnostic and therapeutic capacity for osteoporosis in Shanghai's community health service institutions remains unclear, lacking systematic evaluation and monitoring. Objective To understand the current status of osteoporosis diagnosis, treatment, and management in Shanghai's communi…
Background: Drug use disorder has become a global public health challenge that threatens people's lives and health, increases disease burden, and constrains economic development and social progress. The disease burden caused by different types of drug use varies, and identifying priorities for preve…
Background In accordance with the medical-preventive integration work deployment, and building upon the implementation of basic public health services, Longhua District of Shenzhen launched a pilot program of "digitalization + health management" generalist-specialist collaborative services across th…
The prevalence of obesity-related hypertension has risen markedly worldwide, emerging as a focal point of attention in the current medical community. Obesity increases the difficulty of controlling hypertension, promotes cardiovascular and cerebrovascular injury, and aggravates disease burden. Abnor…
Background: Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant widely used for the treatment of major depression, generalized anxiety disorder, and depression comorbidities. The Chinese Expert Consensus on the Clinical Application of Therapeutic Drug Monitoring in Psy…
Background In recent years, diabetic foot has become a significant cause of disability and mortality among diabetic patients. With advancements in era and technology, the understanding and research of diabetic foot in both modern medicine and traditional Chinese medicine have gradually deepened, fur…
Background: Acute myocardial infarction (AMI) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) is the preferred clinical treatment for most AMI patients; however, they still face a high risk of heart failure (HF) after surgery, with poor prognosis that severe…
Background Endoscopic retrograde cholangiopancreatography (ERCP) is the standard method for diagnosing and treating pancreaticobiliary diseases, but post-ERCP pancreatitis (PEP) represents a serious complication. Non-steroidal anti-inflammatory drugs (NSAIDs) may play a role in PEP prevention due to…
Background Mycoplasma pneumoniae pneumonia (MPP) is a common community-acquired pneumonia in children in China. Its clinical features and prognosis are closely related to age and imaging progression, yet systematic studies combining age stratification with imaging analysis remain insufficient. Objec…
Brand plays an increasingly important role in the management of community health service centers. By implementing brand strategy, these centers can attract more residents to "seek treatment for minor illnesses within the community," which is of great significance for the rational allocation of medic…
Background: For patients with heart failure, early assessment and prompt treatment can prevent adverse cardiac events, and effective diagnostic evaluation tools are particularly important for such patients; phonocardiography (ACG) serves as an efficient and non-invasive bedside screening tool for as…
Intracerebral hemorrhage (ICH) is a stroke subtype with high mortality and disability rates. Ferroptosis plays a crucial role in secondary injury following ICH. Mitochondria, as the hub of cellular metabolism and energy production, are critically involved in ferroptosis. Investigating the role of mi…
The high-quality development of national basic public health services is constrained by bottlenecks including insufficient high-quality resources at the primary level and limited diagnostic and treatment capacities. In accordance with the deployment of medical-preventive integration, and relying on …
Background Post-stroke dysphagia is one of the common and serious complications of stroke, which can significantly reduce patients' quality of life and increase mortality risk. Current research suggests that multiple factors are associated with the prognosis of post-stroke dysphagia, but the quality…
Arterial pressure, structure, and function assessment constitutes an essential component of cardiovascular health management. In recent years, various non-invasive evaluation techniques have been applied in clinical practice; however, the usage details, advantages, and limitations of these technolog…
Background: Heart failure (HF) represents a major chronic disease that seriously endangers global health, with coronary heart disease (CHD) being its most common cause. Constructing risk prediction models based on risk factors for HF complicating CHD can assist healthcare professionals in early iden…
Background: Blood stasis syndrome is an important concurrent syndrome of primary Sjögren's syndrome (pSS), yet research on its quantitative characteristics and clinical associations remains insufficient. Objective: To investigate the quantitative characteristics of blood stasis syndrome in pSS patie…
Background Hypertension is a major cardiovascular disease. The Life's Essential 8 (LE8) score, a recently proposed cardiovascular health assessment indicator, and its relationship with the risk of hypertension remains unclear. Objective To investigate the relationship between LE8 score and the risk …
Background: In recent years, the incidence and prevalence of metabolic-associated fatty liver disease (MAFLD) have been increasing annually, with over a quarter of the global population affected by MAFLD. Type 2 diabetes mellitus (T2DM) is closely associated with MAFLD; however, there are currently …
Background The high incidence of type 2 diabetes mellitus in older adults has become a severe global public health problem. Diabetes causes substantial damage to cognitive function, and there remains a lack of simple indicators for its early monitoring and identification, necessitating further explo…
Background: Alzheimer's disease (AD) is a complex neurodegenerative disease that imposes a heavy burden on patients and their families. In recent years, clinical studies on traditional Chinese medicine preparations for AD treatment have been increasing continuously, yet the evidence base remains unc…
Background: As China's aging process continues to advance, health shock issues among the middle-aged and elderly population have increasingly become a significant social problem. Objective: To comprehensively understand the health shock situation among middle-aged and elderly populations in rural Ni…
Background Wilson's disease (WD) exhibits increased inflammatory levels that are closely associated with cognitive impairment. Studies have demonstrated that activation of the receptor for advanced glycation end products (RAGE)/nuclear factor κB (NF-κB) signaling pathway represents an important infl…
Background Family doctor contract services have been widely promoted nationwide in China, yet challenges remain in further improving both the contract rate and service quality. Consequently, in-depth investigation and analysis of residents' actual demands for family doctor contract services is of pa…
Osteoporosis is a clinically common skeletal disease triggered by multiple factors. Its primary mechanism involves altering the body's inflammatory microenvironment, promoting increased osteoclastogenesis, which subsequently leads to enhanced bone resorption and decreased bone mass. Paradoxical bone…
Background: Current research on physical fitness test scores of high school students predominantly focuses on local areas within provinces or cities, with few large-scale, multi-center studies covering entire regions. The widespread implementation of online and offline blended teaching in schools in…
Dysphagia is a common geriatric syndrome with an increasing incidence year by year, which can easily lead to complications such as aspiration pneumonia and asphyxiation. Currently, research on the status quo of dysphagia and its influencing factors in community-dwelling elderly populations is relati…
Background: In the current rehabilitation environment, emotional problems and cognitive dysfunction in stroke patients are more concealed compared with motor, speech, and swallowing issues, and thus receive insufficient attention in clinical rehabilitation. However, these problems can cause adverse …
Objective To explore the effect of high-intensity interval training (HIIT) on blood glucose control in experimental animals with type 2 diabetes mellitus (T2DM) and to evaluate the quality of the included studies. Methods Literature was obtained by searching PubMed, EMbase, Web of Science, BIOSIS Pr…
