Most papers are machine-translated to English; some are originally in English.
Showing 11 of 11 papers in Biochemistry
As a major global public health issue, the early diagnosis and timely intervention of diabetes are of critical importance. Glycated hemoglobin (HbA1c) serves as a key biomarker for blood glucose management, and its levels exhibit a continuous correlation with the risk of diabetes onset. This study c…
Metabolic-associated fatty liver disease (MAFLD) is a highly prevalent chronic liver disease worldwide, and its progression poses significant health risks. This study, based on publicly available raw urinary proteomic data, comparatively analyzes the differential characteristics of urinary protein p…
Tea and black coffee, as globally widely consumed beverages, play important roles in maintaining organismal health. Since urinary proteins rarely originate directly from beverages, changes in the urine proteome reflect alterations in the organism after being influenced by beverages rather than metab…
This paper is a biochemistry design experiment thesis from Harbin Institute of Technology (Weihai). The experiment employed the 2,6-dichloroindophenol method to determine the vitamin C content in vitamin beverages and effervescent tablets, discussed the feasibility of using pre-made vitamin beverage…
Objective: Pregnancy is a process during which the body's physiological state undergoes profound changes. The normal course of pregnancy is crucial for ensuring proper fetal development and maintaining maternal health. We attempted to explore whether changes in the urinary proteome can reflect the p…
Objective This study addressed the critical concern of clinical surgeons—the efficacy of solid tumor resection. The urinary proteome can sensitively reflect physiological changes in the organism. This study explored changes in the urinary proteome of mice with MC38 subcutaneous tumors following rese…
Abstract Objective: Escitalopram requires approximately 12 weeks to demonstrate efficacy in the treatment of depression. We sought to explore the prediction of drug efficacy before medication administration using a urinary proteome approach. Methods: We selected urine samples from 10 good responders…
Proteins in urine are enriched through multiple filtrations of plasma by the glomeruli, and the information they contain can sensitively reflect changes in the human body. Following vaccination, blood antibody titers and seroconversion rates are typically assessed at 2–4 weeks; could urine enable ea…
[Objective] This study aims to investigate the effects of hypoxia on the rat urinary proteome and identify changes in urinary proteins associated with hypoxic stress. [Methods] This study employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to screen for differential urinary proteins i…
Hypertension is a multifactorial complex disease associated with genetic and environmental factors that has become one of the most serious public health challenges. Despite progress in blood pressure reduction, the diagnosis and treatment of hypertension remain limited due to insufficient investigat…
[Objective] To observe the dynamic changes in the urinary proteome across different disease stages in a DEN-induced inflammation-cancer model of hepatocellular carcinoma. [Methods] In this study, a rat inflammation-cancer model of hepatocellular carcinoma was established via intraperitoneal injectio…
